| 中文名稱 | 干擾素β抗體 |
| 別 名 | Interferon beta; Fibroblast interferon; IFB; IFF; IFN beta; IFNB 1; IFNB; IFNB1; Interferon beta 1 fibroblast; Interferon beta precursor; MGC96956. |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 免疫學(xué) 干擾素 |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human, |
| 產(chǎn)品應(yīng)用 | ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 20kDa |
| 細(xì)胞定位 | 分泌型蛋白 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human IFN-Beta:101-187/187 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 產(chǎn)品介紹 | Interferon-Beta, IFN-Beta mainly by the fibroblast cell factor, belonging to a single gene encodes a protein that can interfere with the virus RNA or DNA replication and inhibit virus growth, and significantly enhance NK cell activity, through the promotion of MHC Ⅰ molecule expression and enhance the CTL of the virus-infected cells role in the identification and destruction. Function: Has antiviral, antibacterial and anticancer activities. Subunit: Monomer. Subcellular Location: Secreted. Similarity: Belongs to the alpha/beta interferon family. SWISS: P01574 Gene ID: 3456 Database links: Entrez Gene: 3456 Human Omim: 147640 Human SwissProt: P01574 Human Unigene: 93177 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. β型干擾素(Interferon-β,IFN-β)是主要由成纖維細(xì)胞產(chǎn)生的細(xì)胞因子,屬于單一基因編碼產(chǎn)生的蛋白質(zhì),可通過(guò)干擾病毒RNA或DNA復(fù)制而抑制病毒生長(zhǎng),并可顯著增強(qiáng)NK細(xì)胞殺傷活性,通過(guò)促進(jìn)MHCⅠ類分子表達(dá)而增強(qiáng)CTL對(duì)病毒感染細(xì)胞的識(shí)別和殺傷作用. |
| 產(chǎn)品圖片 |  Paraformaldehyde-fixed, paraffin embedded (human pancreatic cancer); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (IFN-Beta/Ifnb1) Polyclonal Antibody, Unconjugated (bs-0787R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining. Paraformaldehyde-fixed, paraffin embedded (human liver carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (IFN-Beta/Ifnb1) Polyclonal Antibody, Unconjugated (bs-0787R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining. Tissue/cell: human colon cancer; 4% Paraformaldehyde-fixed and paraffin-embedded;Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-IFN-Beta/Ifnb1 Polyclonal Antibody, Unconjugated(bs-0787R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining  Tissue/cell: human colon cancer; 4% Paraformaldehyde-fixed and paraffin-embedded;Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-IFN-Beta/Ifnb1 Polyclonal Antibody, Unconjugated(bs-0787R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining  Paraformaldehyde-fixed, paraffin embedded (human endometrial carcinoma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (IFN-Beta/Ifnb1) Polyclonal Antibody, Unconjugated (bs-0787R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining. |
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