| 中文名稱 | 磷酸化離子通道蛋白Kv3.1抗體 |
| 別 名 | KCNC1 (phospho S503); p-KCNC1 (phospho Ser503); C230009H10Rik; FLJ41162; FLJ42249; FLJ43491; Kcr2 1; KShIIIB; Kv3.1; Kv4; MGC129855; NGK2; Potassium voltage-gated channel subfamily C member 1; Shaw; Voltage gated potassium channel; KCNC1_RAT; Voltage gated potassium channel subunit Kv3.1; Voltage-gated potassium channel subunit Kv3.1; KCNC1_RAT. |
| 產(chǎn)品類型 | 磷酸化抗體 |
| 研究領(lǐng)域 | 細胞生物 免疫學(xué) 神經(jīng)生物學(xué) 通道蛋白 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human, (predicted: Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep, ) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 58kDa |
| 細胞定位 | 細胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated Synthesised phosphopeptide derived from rat KCNC1 around the phosphorylation site of Ser503:AD(p-S)KL |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| PubMed | PubMed |
| 產(chǎn)品介紹 | KCNC1 mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. It forms a heteromultimer with KCNG3, KCNG4 and KCNV2. Function: This protein mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient. Subunit: Heteromultimer with KCNG3, KCNG4 and KCNV2 (By similarity). Subcellular Location: Membrane; Multi-pass membrane protein. Similarity: Belongs to the potassium channel family. C (Shaw) (TC 1.A.1.2) subfamily. Kv3.1/KCNC1 sub-subfamily. SWISS: P25122 Gene ID: 25327 Database links: Entrez Gene: 3746 Human Entrez Gene: 16502 Mouse Entrez Gene: 25327 Rat Omim: 176258 Human SwissProt: P48547 Human SwissProt: P15388 Mouse SwissProt: P25122 Rat Unigene: 303870 Human Unigene: 552896 Human Unigene: 249386 Mouse Unigene: 33095 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品圖片 |  Sample:HL60(Human) Cell Lysate at 30 ug Primary: Anti- phospho-KCNC1 (Ser503) (bs-5403R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 58 kD Observed band size: 58 kD  Sample:Hela(Human) Cell Lysate at 30 ug Primary: Anti- phospho-KCNC1 (Ser503) (bs-5403R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 58 kD Observed band size: 58 kD  Sample:U2OS(Human) Cell Lysate at 30 ug Hela (Human) Cell Lysate at 30 ug Primary: Anti- phospho-KCNC1 (Ser503) (bs-5403R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 58 kD Observed band size: 58 kD  Sample:HL60(Human) Cell Lysate at 30 ug > Primary: Anti- phospho-KCNC1 (Ser503) (bs-5403R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 58 kD Observed band size: 58 kD |
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