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G蛋白偶聯(lián)受體GPR92蛋白抗體

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英文名稱 GPR92
中文名稱 G蛋白偶聯(lián)受體GPR92蛋白抗體
別    名 GPCR GPR92; G-protein coupled receptor 92; G-protein coupled receptor 93; GPR92; GPR93; KPG_010; LPA receptor 5; LPA-5; LPA5; LPAR5; Lysophosphatidic acid receptor 5; LPAR5_HUMAN; GPCR 92.  
研究領(lǐng)域 細(xì)胞生物  免疫學(xué)  信號轉(zhuǎn)導(dǎo)  G蛋白偶聯(lián)受體  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse, Rat,  (predicted: Human, Rabbit, )
產(chǎn)品應(yīng)用 WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復(fù))
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 41kDa
細(xì)胞定位 細(xì)胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GPR92:121-220/372 
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed PubMed
產(chǎn)品介紹 This gene encodes a member of the rhodopsin class of G protein-coupled transmembrane receptors. This protein transmits extracellular signals from lysophosphatidic acid to cells through heterotrimeric G proteins and mediates numerous cellular processes. Many G protein receptors serve as targets for pharmaceutical drugs. Transcript variants of this gene have been described.[provided by RefSeq, Dec 2008]

Function:
Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Tissue Specificity:
Not expressed in frontal cortex, basal forebrain, caudate putamen, thalamus, or hippocampus.

Similarity:
Belongs to the G-protein coupled receptor 1 family.

SWISS:
Q9H1C0

Gene ID:
57121

Database links:

Entrez Gene: 57121 Human

Omim: 606926 Human

SwissProt: Q9H1C0 Human

Unigene: 155538 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
 
產(chǎn)品圖片 Protein: cerebellum(mouse) lyates at 40ug;
Primary: Rabbit Anti-GPR92 (bs-15366R) at 1:300;
Secondary: 800CW Conjugated Goat (polyclonal) Anti-Rabbit IgG(H+L) at 1: 10000;
Predicted band size:41 kD Observed band size:51 kDProtein: brain(mouse) lyates at 40ug;
Primary: Rabbit Anti-GPR92 (bs-15366R) at 1:300;
Secondary: 800CW Conjugated Goat (polyclonal) Anti-Rabbit IgG(H+L) at 1: 10000;
Predicted band size:41 kD Observed band size:51 kDTissue/cell: rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
Incubation: Anti-GPR92 Polyclonal Antibody, Unconjugated(bs-15366R) 1:500, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
Tissue/cell: rat lung tissue; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
Incubation: Anti-GPR92 Polyclonal Antibody, Unconjugated(bs-15366R) 1:500, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining

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