中文名稱 鈣結(jié)合蛋白重組兔單克隆抗體
別 名 29 kDa calbindin; CAB 29; CAB29; CAL 2; CAL2; CALB 2; CALB2; Calbindin 2 29kDa; Calbindin 2; Calbindin D29K; Calbindin2; CR; CALB2_HUMAN; Calretinin.
研究領(lǐng)域 腫瘤 神經(jīng)生物學(xué) 結(jié)合蛋白
抗體來(lái)源 Rabbit
克隆類型 Monoclonal
克 隆 號(hào) 4A3
交叉反應(yīng) (predicted: Human, Mouse, Rat, )
產(chǎn)品應(yīng)用 WB=1:200-500 IHC-P=1:50-200 IHC-F=1:50-200 (石蠟切片需做抗原修復(fù))
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 29kDa
細(xì)胞定位 細(xì)胞漿 細(xì)胞膜
性 狀 Liquid
濃 度 1mg/ml
免 疫 原 Recombinant human Calretinin protein:
亞 型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed PubMed
產(chǎn)品介紹 Calretinin is a calcium-binding protein which is abundant in auditory neurons. It belongs to the calbindin family. Calbindin 2 (calretinin), closely related to calbindin 1, is an intracellular calcium-binding protein belonging to the troponin C superfamily. Calbindin 1 is known to be involved in the vitamin-D-dependent calcium absorption through intestinal and renal epithelia, while the function of neuronal calbindin 1 and calbindin2 is poorly understood. The sequence of the calbindin 2 cDNA reveals an open reading frame of 271 codons coding for a protein of 31,520 Da, and shares 58% identical residues with human calbindin1.
Function:
Calretinin is a calcium-binding protein which is abundant in auditory neurons.
Tissue Specificity:
Brain.
Similarity:
Belongs to the calbindin family.
Contains 6 EF-hand domains.
SWISS:
P22676
Gene ID:
794
Database links:
Entrez Gene: 396255 ChickenEntrez Gene: 794 HumanEntrez Gene: 12308 MouseEntrez Gene: 117059 RatEntrez Gene: 393684 ZebrafishOmim: 114051 HumanSwissProt: P07090 ChickenSwissProt: P22676 HumanSwissProt: Q08331 MouseSwissProt: P47728 RatUnigene: 106857 HumanUnigene: 2755 MouseUnigene: 10321 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human