中文名稱 磷酸化酪氨酸激酶B(Tyr817)重組兔單克隆抗體
別 名 TrkB(Y817); TrkB (phospho Y817); p-TrkB (phospho Y817); TrkB (Phospho-Tyr817); TrkB (Phospho Tyr817); TrkB (Phospho-Y817); p-TrkB(Tyr817); AI848316; BDNF tropomyosine receptor kinase B; BDNF/NT 3 growth factors receptor; BDNF/NT-3 growth factors receptor; Brain derived neurotrophic factor receptor; C030027L06Rik; EC 2.7.10.1; GP145 TrkB; GP145-TrkB; GP145-TrkB/GP95-TrkB; GP95 TrkB; Neurotrophic tyrosine kinase receptor type 2; Neurotrophin receptor tyrosine kinase type 2; NTRK 2; Ntrk2; NTRK2_HUMAN; Obesity, hyperphagia, and developmental delay, included; RATTRKB1; Tkrb; Trk B; Trk-B; TRKB; TrkB tyrosine kinase; TRKB1; Tropomyosin related kinase B; tyrosine kinase receptor B; Tyrosine receptor kinase B.
產品類型 磷酸化抗體
研究領域 腫瘤 細胞生物 免疫學 神經(jīng)生物學 信號轉導 轉錄調節(jié)因子 激酶和磷酸酶
抗體來源 Rabbit
克隆類型 Monoclonal
克 隆 號 2A1
交叉反應 (predicted: Human, Mouse, Rat, )
產品應用 WB=1:1000-2000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 IF=1:50-200 （石蠟切片需做抗原修復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 90kDa
細胞定位 細胞漿 細胞膜
性 狀 Liquid
濃 度 1mg/ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human TrkB around the phosphorylation site of Tyr817:PV(p-Y)LD
亞 型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMed PubMed
產品介紹 This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternate transcriptional splice variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Function:
Receptor tyrosine kinase involved in the
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