英文名稱TRAF3IP3
中文名稱T3JAM蛋白抗體
別 名T3JAM; TRAF3 interacting JNK activating modulator; T3JAM_HUMAN; TRAF3 interacting protein 3.
研究領域細胞生物 信號轉導 跨膜蛋白
抗體來源Rabbit
克隆類型Polyclonal
交叉反應(predicted: Human, )
產(chǎn)品應用ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量64kDa
細胞定位細胞膜
性 狀Liquid
濃 度1mg/ml
免 疫 原KLH conjugated synthetic peptide derived from human TRAF3IP3:501-551/551
亞 型IgG
純化方法affinity purified by Protein A
儲 存 液0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
PubMedPubMed
產(chǎn)品介紹The gene encodes a protein that mediates cell growth by modulating the c-Jun N-terminal kinase signal transduction pathway. The encoded protein may also interact with a large multi-protein assembly containing the phosphatase 2A catalytic subunit. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
Function:
This protein may function as an adapter molecule that regulates TRAF3-mediated JNK activation.
Subunit:
Binds to the isoleucine zipper of TRAF3 via its coiled-coil domain (By similarity).
Subcellular Location:
Membrane; single pass type IV membrane protein
SWISS:
Q9Y228
Gene ID:
80342
Database links:
Entrez Gene: 80342 Human
SwissProt: Q9Y228 Human
SwissProt: Q8C0G2 Mouse
Unigene: 147434 Human
Unigene: 261259 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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