| 產(chǎn)品編號(hào) | Ys-2572R |
| 英文名稱 | FPR1 |
| 中文名稱 | 甲酸基肽受體1抗體 |
| 別 名 | Formyl peptide receptor 1; fMet Leu Phe receptor; FMLP; FMLP Receptor; FPR 1; FPR; N formyl peptide chemoattractant receptor; N formyl peptide receptor; N formylpeptide chemoattractant receptor; fMet-Leu-Phe receptor; FMLPR; FPR; FPR receptor; FPR1; FPR1_HUMAN; N formylpeptide chemoattractant receptor; N-formyl peptide receptor; N-formylpeptide chemoattractant receptor. |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human, (predicted: Mouse, Rat, ) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 （石蠟切片需做抗原修復(fù)） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 39kDa |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human FPR1: 51-150/350 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 | This gene encodes a G protein-coupled receptor of mammalian phagocytic cells that is a member of the G-protein coupled receptor 1 family. The protein mediates the response of phagocytic cells to invasion of the host by microorganisms and is important in host defense and inflammation.[provided by RefSeq, Jul 2010] Function: High affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Subcellular Location: Cell membrane; Multi-pass membrane protein. Tissue Specificity: Neutrophils. Similarity: Belongs to the G-protein coupled receptor 1 family. SWISS: P21462 Gene ID: 2357 轉(zhuǎn)錄調(diào)節(jié)因子（Transcriptin Regulators） FPR1屬于G蛋白偶聯(lián)受體家族成員，參與細(xì)胞信號(hào)傳導(dǎo)，激活MAPK通路，免疫應(yīng)答。 |
| 產(chǎn)品圖片 |  Sample: Lane 1: U87MG (Human) Cell Lysate at 30 ug Lane 2: U251 (Human) Cell Lysate at 30 ug Lane 3: U937 (Human) Cell Lysate at 30 ug Lane 4: SW480 (Human) Cell Lysate at 30 ug Primary: Anti-FPR1 (bs-2572R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 60 kD Observed band size: 60 kD |
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