| 產(chǎn)品編號 | Ys-2624R |
| 英文名稱 | IL22R |
| 中文名稱 | 白介素22受體抗體 |
| 別 名 | IL-22R; CRF2 9; IL22 Receptor Alpha; cytokine receptor classII member 9; cytokine receptor family 2 member 9; IL-22 receptor subunit alpha-1; IL-22R-alpha-1; IL22R; IL22R1; IL22RA1; ILTIF R1 chain; Interleukin 22 Receptor alpha 1; Interleukin 22 Receptor; Interleukin-22 receptor subunit alpha-1; ZcytoR11; I22R1_HUMAN; IL-22 receptor subunit alpha-1; IL-22RA1; Cytokine receptor class-II member 9; Cytokine receptor family 2 member 9; CRF2-9. |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human, Mouse, (predicted: Rat, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig, ) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000 ELISA=1:5000-10000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 61kDa |
| 細胞定位 | 細胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human IL-22R: 41-150/574 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 | The protein encoded by this gene belongs to the class II cytokine receptor family, and has been shown to be a receptor for interleukin 22 (IL22). IL22 receptor is a protein complex that consists of this protein and interleukin 10 receptor, beta (IL10BR/CRFB4), a subunit also shared by the receptor complex for interleukin 10 (IL10). This gene and interleukin 28 receptor, alpha (IL28RA) form a cytokine receptor gene cluster in the chromosomal region 1p36. [provided by RefSeq, Jul 2008]. Function: Component of the receptor for IL20, IL22 and IL24. Component of IL22 receptor formed by IL22RA1 and IL10RB enabling IL22 signaling via JAK/STAT pathways. IL22 also induces activation of MAPK1/MAPK3 and Akt kinases pathways. Component of one of the receptor for IL20 and IL24 formed by IL22RA1 and IL20RB also signaling through STATs activation. Mediates IL24 antiangiogenic activity as well as IL24 inhibitory effect on endothelial cell tube formation and differentiation. Subunit: Heterodimer with IL10RB and with IL20RB. Subcellular Location: Membrane; Single-pass type I membrane protein. Tissue Specificity: Expressed in kidney, liver and lung. Similarity: Belongs to the type II cytokine receptor family. Contains 2 fibronectin type-III domains. SWISS: Q8N6P7 Gene ID: 58985 |
| 產(chǎn)品圖片 |  Sample: Lane1: Liver(Mouse) Lysate at 30 ug Lane2: Intestinal(Mouse) Lysate at 30 ug Primary: Anti-IL22R (bs-2624R) at 1:300 dilution; Secondary: HRP conjugated Goat-Anti-Rabbit IgG(bs-0295G-HRP) at 1: 5000 dilution; Predicted band size : 61kD Observed band size : 61kD  Sample: placenta (Mouse) Lysate at 40 ug Primary: Anti-IL22R (Bs-2624R) at 1/300 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 61 kD Observed band size: 65 kD |
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