| 產(chǎn)品編號(hào) | Ys-0590R |
| 英文名稱 | CYGB |
| 中文名稱 | 細(xì)胞球蛋白抗體 |
| 別 名 | Cytoglobin; HGB; STAP; Histoglobin; HGb; cell activation-associated protein; CYGB_HUMAN. |
| 研究領(lǐng)域 | 細(xì)胞生物 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human, Rat, (predicted: Mouse, Chicken, Dog, Cow, Horse, ) |
| 產(chǎn)品應(yīng)用 | ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 （石蠟切片需做抗原修復(fù)） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 21kDa |
| 細(xì)胞定位 | 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human cytoglobin: 87-132/190 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 | This gene encodes a globin protein found in vertebrate cells. The encoded protein is described as a hexacoordinate hemoglobin which binds ligand differently from the pentacoordinate hemoglobins involved in oxygen transport, and may be involved in protection during oxidative stress. This gene is located on chromosome 17 in the same region as a retinal gene which is mutated in progressive rod-cone degeneration, but in the opposite orientation. [provided by RefSeq, Jan 2012] Function: May have a protective function during conditions of oxidative stress. May be involved in intracellular oxygen storage or transfer. Subunit: Homodimer; disulfide-linked. Subcellular Location: Cytoplasm. Tissue Specificity: Ubiquitously expressed. Highest expression in heart, stomach, bladder and small intestine. Similarity: Belongs to the globin family. SWISS: Q8WWM9 Gene ID: 114757 細(xì)胞球蛋白Cygb是最近發(fā)現(xiàn)的脊椎動(dòng)物球蛋白超家族的一員,在體內(nèi)分布廣泛。 有學(xué)者認(rèn)為：Cygb的確切功能尚不十分清楚,目前主要有攜氧與儲(chǔ)氧、氧感受器、活性氧基團(tuán)和NO的清道夫、NADH氧化酶或過氧化氫酶樣作用和參與膠原形成等假說。 |
| 產(chǎn)品圖片 | Tissue/cell: rat brain tissue; 4% Paraformaldehyde-fixed and paraffin-embedded; Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min; Incubation: Anti-Cygb Polyclonal Antibody, Unconjugated(bs-0590R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining |
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