| 產(chǎn)品編號 | ys-24627R |
| 英文名稱 | MYCL |
| 中文名稱 | Myc基因肺癌相關蛋白抗體 |
| 別 名 | l myc protein; l myc 1 proto oncogene; L myc 1 proto-oncogene protein; Myc related gene from lung cancer; MYCL 1; MYCL1; LMYC; BHLHE38; Protein L-Myc-1; oncogene lmyc; v myc avian myelocytomatosis viral oncogene homolog 1 lung carcinoma derived; l-Myc; MYCL1_HUMAN. |
| 研究領域 | 腫瘤 免疫學 染色質(zhì)和核信號 轉(zhuǎn)錄調(diào)節(jié)因子 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應 | Rat, (predicted: Human, Mouse, Dog, Pig, Cow, Horse, Rabbit, Sheep, ) |
| 產(chǎn)品應用 | ELISA=1:5000-10000 IHC-P=1:400-800 （石蠟切片需做抗原修復） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 40kDa |
| 細胞定位 | 細胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human L-Myc: 101-200/364 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 | Cellular DNA-binding proteins encoded by the c-myc genes. They are normally involved in nucleic acid metabolism and in mediating the cellular response to growth factors. Elevated and deregulated (constitutive) expression of c-myc proteins can cause tumorigenesis. The MYCL1 gene encodes a protein which is associated with lung cancer in idiopathic pulmonary fibrosis. Subunit: Efficient DNA binding requires dimerization with another bHLH protein. Binds DNA as an heterodimer with MAX. Subcellular Location: Nucleus. Similarity: Contains 1 basic helix-loop-helix (bHLH) domain. SWISS: P12524 Gene ID: 4610 |
| 產(chǎn)品圖片 |  Paraformaldehyde-fixed, paraffin embedded (Rat placenta); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (L-Myc) Polyclonal Antibody, Unconjugated (bs-24627R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.  Paraformaldehyde-fixed, paraffin embedded (Rat bladder); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (L-Myc) Polyclonal Antibody, Unconjugated (bs-24627R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining. |
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