| 產(chǎn)品編號(hào) | Ys-2565R |
| 英文名稱 | Ly75/CD205 |
| 中文名稱 | 淋巴細(xì)胞抗原75抗體 |
| 別 名 | C-type lectin domain family 13 member B; CD 205; CD205; CD205 antigen; CLEC 13B; CLEC13B; DEC 205; DEC-205; DEC205; gp200; gp200 MR6; gp200-MR6; LY 75; Ly-75; LY75; LY75_HUMAN; Lymphocyte antigen 75; Renal Cell Carcinoma (gp200). |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞類型標(biāo)志物 b-淋巴細(xì)胞 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, Mouse, Rat, Dog, Cow, Rabbit, Guinea Pig, ) |
| 產(chǎn)品應(yīng)用 | ELISA=1:5000-10000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 195kDa |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human DEC-205: 601-700/1722 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 | Ly75 is expressed in spleen, thymus, colon and peripheral blood lymphocytes and causes reduced proliferation of B-lymphocytes as well as acting as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen-processing compartment. Ly75 is also detected in myeloid and B lymphoid cell lines and isoforms 2 and 3 are expressed in Hodgkin and Reed-Sternberg (HRS) cells (malignant Hodgkin lymphoma cells). Function: Acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen-processing compartment. Causes reduced proliferation of B-lymphocytes. Subcellular Location: Membrane; Single-pass type I membrane protein. Tissue Specificity: Expressed in spleen, thymus, colon and peripheral blood lymphocytes. Detected in myeloid and B-lymphoid cell lines. Isoform 2 and isoform 3 are expressed in malignant Hodgkin lymphoma cells called Hodgkin and Reed-Sternberg (HRS) cells. Post-translational modifications: N-glycosylated. Similarity: Contains 10 C-type lectin domains. Contains 1 fibronectin type-II domain. Contains 1 ricin B-type lectin domain. |
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