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間隙連接蛋白36抗體

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產(chǎn)品編號 Ys-1266R
英文名稱 Connexin-36
中文名稱 間隙連接蛋白36抗體
別    名 Connexin 36; CX36; Gap junction protein alpha 9; gap junction protein, alpha 9, 36kDa; GJA9; MGC138315; MGC138319; CXD2_HUMAN.  
研究領(lǐng)域 神經(jīng)生物學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human,  (predicted: Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Guinea Pig, )
產(chǎn)品應(yīng)用 WB=1:500-2000 ELISA=1:5000-10000 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 36kDa
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Connexin-36: 201-321/321 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes a member of the connexin protein family. Connexins are gap junction proteins which are arranged in groups of 6 around a central pore to form a connexon, a component of the gap junction intercellular channel. The channels formed by this protein allow cationic molecule exchange between human beta cells and may function in the regulation of insulin secretion. [provided by RefSeq, Oct 2012]

Function:
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell.

Subunit:
A connexon is composed of a hexamer of connexins.

Subcellular Location:
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.

Tissue Specificity:
Highly expressed in neurons.

Similarity:
Highly expressed in neurons.
Belongs to the connexin family. Delta-type subfamily.

SWISS:
Q9UKL4

Gene ID:
57369




間隙連接是神經(jīng)系統(tǒng)構(gòu)成電突觸的結(jié)構(gòu)基礎(chǔ),參與調(diào)控神經(jīng)沖動纖毫傳遞和復(fù)雜神經(jīng)網(wǎng)絡(luò)的整合,而Cx36是唯一一個在神經(jīng)系統(tǒng)中優(yōu)先表達的Cx,因此成為電生理研究主要蛋白。
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