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發(fā)狀分裂相關(guān)增強(qiáng)子-5抗體

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產(chǎn)品編號(hào) Ys-23071R
英文名稱 HES5
中文名稱 發(fā)狀分裂相關(guān)增強(qiáng)子-5抗體
別    名 BHLHB38; Transcription factor HES-5; Class B basic helix-loop-helix protein 38 (bHLHb38); Hairy and enhancer of split 5; HES 5; HES5 protein; MGI:104876; HES5_HUMAN.   
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse,  (predicted: Rat, Dog, Cow, Horse, )
產(chǎn)品應(yīng)用 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100 IF=1:100-500 (石蠟切片需做抗原修復(fù))
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 18kDa
細(xì)胞定位 細(xì)胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human HES5: 31-130/166 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes a member of a family of basic helix-loop-helix transcriptional repressors. The protein product of this gene, which is activated downstream of the Notch pathway, regulates cell differentiation in multiple tissues. Disruptions in the normal expression of this gene have been associated with developmental diseases and cancer. [provided by RefSeq, Dec 2008]

Function:
Transcriptional repressor of genes that require a bHLH protein for their transcription

Subunit:
Transcription repression requires formation of a complex with a corepressor protein of the Groucho/TLE family.

Subcellular Location:
Nucleus.

Tissue Specificity:
Expressed in fetal heart and brain tumors.

Similarity:
Contains 1 basic helix-loop-helix (bHLH) domain.
Contains 1 Orange domain.

SWISS:
Q5TA89

Gene ID:
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