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神經(jīng)纖毛蛋白2抗體

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產(chǎn)品編號 Ys-10241R
英文名稱 Neuropilin 2/NRP2
中文名稱 神經(jīng)纖毛蛋白2抗體
別    名 NRP2; MGC126574; Neuropilin 2; Neuropilin-2; Neuropilin2; NP 2; NP2; NPN 2; NPN2; NRP 2; nrp2; PRO2714; Receptor for VEGF165 and semaphorins class3; Vascular endothelial growth factor 165 receptor 2; VEGF1265R2; NRP2_HUMAN; Vascular endothelial growth factor 165 receptor 2; VEGF165R2

 

抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human,  (predicted: Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應用 WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 99kDa
細胞定位 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Neuropilin 2: 501-600/931 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes a member of the neuropilin family of receptor proteins. The encoded transmembrane protein binds to SEMA3C protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C} and SEMA3F protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F}, and interacts with vascular endothelial growth factor (VEGF). This protein may play a role in cardiovascular development, axon guidance, and tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

Function:
High affinity receptor for semaphorins 3C, 3F, VEGF-165 and VEGF-145 isoforms of VEGF, and the PLGF-2 isoform of PGF.

Subunit:
Heterodimer with NRP1. Binds PLXNB1.

Subcellular Location:
Membrane; Single-pass type I membrane protein.

Tissue Specificity:
Widely expressed.

Similarity:
Belongs to the neuropilin family.
Contains 2 CUB domains.
Contains 2 F5/8 type C domains.
Contains 1 MAM domain.

SWISS:
O60462
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