| 產(chǎn)品編號 | Ys-10033R |
| 英文名稱 | Alpha s1 Casein |
| 中文名稱 | α-s1酪蛋白抗體 |
| 別 名 | Alpha s1 Casein; alpha-S1-casein precursor; Alpha-S1-casein; CSN1S1; CSN1; Bos d 8; Antioxidant peptide; CASA1_BOVIN. |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Cow, Sheep, ) |
| 產(chǎn)品應(yīng)用 | ELISA=1:5000-10000 IHC-F=1:100-500 （石蠟切片需做抗原修復(fù)） not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 23kDa |
| 細(xì)胞定位 | 分泌型蛋白 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from cow Alpha s1 Casein: 75-214/214 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 | alpha-S1-casein, also known as CSN1S1, CSN1 or CASA, is a 185 amino acid secreted protein that is mammary gland-specific and belongs to the alpha-casein family. Existing as a disulfide-linked heterodimer with ⅹ-casein, alpha-S1-casein plays an important role in the ability of milk to transport calcium phosphate, a family of minerals that are key components of bone and teeth. alpha-S1-casein exists as multiple alternatively spliced isoforms and is encoded by a gene which maps to a region on human chromosome 4 that encodes other casein family members. Chromosome 4 houses nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. Defects in some of the genes located on chromosome 4 are associated with Huntington's disease, Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease. Function: Important role in the capacity of milk to transport calcium phosphate. Antioxidant peptide has 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activity. Subcellular Location: Secreted. Tissue Specificity: Mammary gland specific. Secreted in milk. Similarity: Belongs to the alpha-casein family. SWISS: P02662 Gene ID: 282208 |
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