產(chǎn)品編號(hào) | Ys-2761R |
英文名稱 | BRINP1 |
中文名稱 | 膀胱癌缺失基因1抗體 |
別 名 | Deleted in bladder cancer protein 1; deleted in bladder cancer protein 1 precursor; IB3089A; DBC1; DBCCR1; FAM5A; deleted in bladder cancer protein 1 homolog precursor; BMP/retinoic acid-inducible neural-specific protein 1; BRINP; Brinp1; LOC140610; DBC 1; DBC.1; DBCCR1; Deleted in bladder cancer chromosome region candidate 1; Deleted in breast cancer 1; Deleted in breast cancer gene 1 protein; FAM5A; KIAA1967; OTTHUMP00000022751; p30 DBC; p30 DBC protein; Protein FAM5A; DBC1_HUMAN. |
抗體來(lái)源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Mouse, Rat, (predicted: Human, Chicken, Pig, Cow, Horse, Rabbit, ) |
產(chǎn)品應(yīng)用 | WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復(fù)) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 86kDa |
細(xì)胞定位 | 細(xì)胞漿 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human DBC1: 101-200/761 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 | This gene is located within a chromosomal region that shows loss of heterozygosity in some bladder cancers. It contains a 5' CpG island that may be a frequent target of hypermethylation, and it may undergo hypermethylation-based silencing in some bladder cancers. [provided by RefSeq]. Function: Inhibits cell proliferation by negative regulation of the G1/S transition. Mediates cell death which is not of the classical apoptotic type and regulates expression of components of the plasminogen pathway. Subcellular Location: Cytoplasm. Tissue Specificity: Highly expressed in brain. Weakly expressed in heart, lung, skeletal muscle, kidney, thymus, prostate, testis and small intestine. Similarity: Belongs to the FAM5 family. Contains 1 MACPF domain. |
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