產(chǎn)品編號(hào) | Ys-0922R |
英文名稱 | Neurogenin3 |
中文名稱 | 神經(jīng)元素3抗體 |
別 名 | NGN3; NGN-3; neurogenin 3; Neurog3; Neurogenin-3; ATH4B; Atoh5; Math4B; NEUROG3; ngn3; OTTHUMP00000019730; Protein atonal homolog 5; Class A basic helix-loop-helix protein 7; NGN3_HUMAN. |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Human, Mouse, (predicted: Rat, Dog, Cow, Sheep, ) |
產(chǎn)品應(yīng)用 | WB=1:500-2000 ELISA=1:5000-10000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 (石蠟切片需做抗原修復(fù)) not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 23kDa |
細(xì)胞定位 | 細(xì)胞核 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human NGN3: 61-160/214 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存條件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 | Neurogenin-3 (NEUROG3) is expressed in endocrine progenitor cells and is required for endocrine cell development in the pancreas and intestine (Wang et al., 2006 [PubMed 16855267]). It belongs to a family of basic helix-loop-helix transcription factors involved in the determination of neural precursor cells in the neuroectoderm. Function: Involved in neurogenesis. Also required for the specification of a common precursor of the 4 pancreatic endocrine cell types. Subcellular Location: Nucleus. DISEASE: Defects in NEUROG3 are the cause of diarrhea type 4 (DIAR4) [MIM:610370]. DIAR4 is a characterized by severe, life-threatening watery diarrhea associated with generalized malabsorption and a paucity of enteroendocrine cells. Similarity: Contains 1 basic helix-loop-helix (bHLH) domain. |
我要詢價(jià)
*聯(lián)系方式:
(可以是QQ、MSN、電子郵箱、電話等,您的聯(lián)系方式不會(huì)被公開)
*內(nèi)容: