Product Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Partial recombinant protein (300-465 aa) expressed in E. coli.
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
WB - Quality tested
ICC - Verified - Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 2.5 ?g/ml. For immunocytochemistry, a concentration range of 1.0 - 5.0 μg/ml is recommended. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
- AB_2566795 (BioLegend Cat. No. 683302)
Antigen Details
- Structure
- 465 amino acids with a predicted molecular weight of 52.8 kD. Contains a JmjC domain responsible for lysine demethylation of histones.
- Distribution
-
Nucleus and nucleolus.
- Function
- MINA is an oxygenase exerting histone lysine demethylase and ribosomal histidine hydroxylase activities. It is involved in cell proliferation, survival, and T cell differentiation.
- Interaction
- MINA interacts with Srp72, NOP56, RPL10, EIF3E, HNRNPU, RNPS1, RPL35, and RRBP1.
- Biology Area
- Cell Biology, Neuroscience, Neuroscience Cell Markers, Transcription Factors
- Molecular Family
- Nuclear Markers
- Antigen References
-
1. Thakur C, et al. 2015. Genes Cancer 6:288.
2. Pillai MR, et al. 2014. Curr. Opin. Immunol. 31:38.
3. Lian S, et al. 2013. PLoS One 8:e80638.
4. Hemmers S, et al. 2009. Nat. Immunol. 10:806.
5. Lu Y, et al. 2009. Cell Cycle. 8:2101.
6. Tsuneoka M, et al. 2004. Clin. Cancer Res. 10:7347. - Gene ID
- 84864 View all products for this Gene ID
- UniProt
- View information about MINA on UniProt.org
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