Product Details
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Full length mouse Apo-E recombinant protein expressed in E. coli.
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
WB - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 2.5 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.
- Product Citations
-
- RRID
- AB_2565426 (BioLegend Cat. No. 674802)
Antigen Details
- Structure
- 293 amino acids, predicted molecular weight of 34 kD (mature form), and contains one LDL receptor binding domain and two heparin binding regions.
- Function
- Apo-E is a component of serum chylomicron, VLDL, and HDL particles, and mediates lipid metabolism and memory formation.
- Interaction
- SET, KCNMA1, SAA, and PRNP.
- Biology Area
- Cell Biology, Neurodegeneration, Neuroscience, Protein Trafficking and Clearance
- Antigen References
-
1. Hayes EM, et al. 2014. Front Immunol. 5:537.
2. Kim J, et al. 2014. Mol. Cells 37:767.
3. Verghese PB, et al. 2013. Proc. Natl. Acad. Sci. USA 110:E1807.
4. Mahley RW, et al. 2012. Neuron 76:871.
5. Holtzman DM, et al. 2012. Cold Spring Harb. Perspect. Med. 2:a006312.
6. Zhang HL, et al. 2010. Clin. Dev. Immunol. 2010:186813. - Gene ID
- 11816 View all products for this Gene ID
- UniProt
- View information about Apo E on UniProt.org
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