Product Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Human CCR1 transfected cells
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with APC/Cyanine7 under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?L per million cells in 100 ?L staining volume or 5 ?L per 100 ?L of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Red Laser (633 nm)
- RRID
- AB_2876685 (BioLegend Cat. No. 362917) AB_2876685 (BioLegend Cat. No. 362918)
Antigen Details
- Structure
- G-protein coupled receptor, seven transmembrane protein, 41 kD
- Distribution
-
Monocytes, macrophages, subset of T cells, eosinophils
- Function
- Regulates migration of cells in response to CCL3 and CCL5
- Ligand/Receptor
- CCL3 and CCL5
- Cell Type
- Eosinophils, Macrophages, Monocytes, T cells
- Biology Area
- Immunology
- Molecular Family
- CD Molecules, Cytokine/Chemokine Receptors, GPCR
- Antigen References
-
1. Su SB, et al. 1996. J. Leuko. Biol. 60:658.
2. Su S, et al. 1997. Blood. 90:605.
3. Ayehunie S, et al. 1997. Blood. 90:1379.
4. Gerard C, et al. 1997. J. Clin. Invest. 100:2022.
5. Tiffany HL, et al. 1998. J. Immunol. 160:1385.
6. Gilliland CT, et al. 2013. J. Biol. Chem. 288:32194.
7. Bednar F, et al. 2014. J. Immunol. 192:5305. - Gene ID
- 1230 View all products for this Gene ID
- UniProt
- View information about CD191 on UniProt.org
