Product Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Recombinant human CXCL11
- Formulation
- 0.2 ?m filtered in phosphate-buffered solution, pH 7.2, containing no preservative. Endotoxin level is < 0.01 EU/?g of the protein (< 0.001 ng/?g of the protein) as determined by the LAL test.
- Preparation
- The Ultra-LEAF? (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
- Concentration
- The antibody is bottled at the concentration indicated on the vial, typically between 2 mg/mL and 3 mg/mL. Older lots may have also been bottled at 1 mg/mL. To obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C. This Ultra-LEAF? solution contains no preservative; handle under aseptic conditions.
- Application
-
Neut - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by neutralization of chemotaxis induced by recombinant human CXCL11 (ITAC) (Cat. No. 574904) at 15 ng/mL on mouse Baf3-mCXCR3 transfectant chemoattractant cells. ND50 range: 0.01 - 0.1 ?g/mL. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
- AB_2892512 (BioLegend Cat. No. 945403) AB_2892512 (BioLegend Cat. No. 945404)
Antigen Details
- Structure
- Chemokine
- Distribution
-
T lymphocytes, keratinocytes, monocytes, macrophages, fibroblasts, and endothelial cells
- Function
- Chemoattractant for activated T lymphocytes and NK cells, stimulation of IFN-γ expression, inhibition of angiogenesis
- Interaction
- Activated T cells, Th1 cells, regulatory T cells, NK cells, endothelial cells
- Ligand/Receptor
- CXCR3-A, CXCR3-B, CXCR7
- Antigen References
-
1.Widney DP, et al. 2000. J. Immunol. 164:6322.
2. Meyer M, et al. 2000. Cytogenet. Cell Genet. 88:278.
3. Loetscher P, et al. 2001. J. Biol. Chem. 276(5):2986-91. - Gene ID
- 6373 View all products for this Gene ID
- UniProt
- View information about CXCL11 on UniProt.org
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