Product Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- GP130 (23-619aa) recombinant protein
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Red Laser (633 nm)
- Product Citations
-
- RRID
- AB_2563403 (BioLegend Cat. No. 362005) AB_2563404 (BioLegend Cat. No. 362006)
Antigen Details
- Structure
- 130 kD type I transmembrane glycoprotein.
- Distribution
-
T cells, activated B cells, monocytes, plasma cells, endothelial cells and epithelial cells.
- Function
- Common β subunit of IL-6 receptor family, plays a role in signal transduction.
- Ligand/Receptor
- IL-6, IL-11, OSM, CNTF, CT-1, NP, IL-27.
- Cell Type
- B cells, Endothelial cells, Epithelial cells, Monocytes, Plasma cells, T cells
- Biology Area
- Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
1. Arzt E, et al. 2001. J. Clin. Invest. 108:1729.
2. Bravo J, et al. 2000. EMBO J. 19:2399.
3. Wang XJ, et al. 1998. Blood 91:3308.
4. Hibi. M, et al. 1990. Cell. 63:1149.
5. Schlossman S, et al. 1995. ed. Leukocyte Typing V. New York. Oxford University Press. - Gene ID
- 3572 View all products for this Gene ID
- UniProt
- View information about CD130 on UniProt.org
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