Product Details
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Recombinant mouse OMG
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
WB - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.2 - 2.0 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
This antibody also detects a non-specific protein of approximately 145 kD in the mouse brain. Clone A16003A does not cross-react with human and rat (in-house tested).
- RRID
- AB_2650732 (BioLegend Cat. No. 694602)
Antigen Details
- Structure
- 440 amino acids, and predicted molecular weight is 49 kD. Due to N-glycosylation (11 glycosylation sites), the observed molecular weight ranges from 90 kD to 120 kD.
- Distribution
- Cell membrane
- Function
- Cell adhesion molecule contributing to the interactive process required for myelination in the central nervous system.
- Interaction
- RTN4R, Central nervous system (CNS) axons.
- Ligand/Receptor
- NgR1 and PirB
- Biology Area
- Cell Adhesion, Cell Biology
- Antigen References
-
1. Habib AA, et al. 1998. Oncogene 12:1525-31.
2. Wang KC, et al. 2002. Nature 417:941-944.
3. Kottis V, et al. 2002. J. Neurochem. 82:1566-9.
4. Huang JK, et al. 2005. Science 310(5755):1813-7.
5. Atwal JK, et al. 2008. Science 322(5903):967-70.
6. Raiker SJ, et al. 2010. J. Neurosci. 30:12432-45.
7. Huang JY, et al. 2012. Brain Res. 1437:1-15.
8. Kempf A, et al. 2014. PLoS Biol. 12:e1001763. - Gene ID
- 18377 View all products for this Gene ID
- UniProt
- View information about Oligodendrocyte-myelin glycoprotein on UniProt.org
