Product Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Human recombinant VCAM-1/FC
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
WB - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.002 - 0.1 ?g/mL (1:5000-1:250000 diluted). It is recommended that the reagent be titrated for optimal performance for each application.
- Product Citations
-
- RRID
- AB_2687276 (BioLegend Cat. No. 698201) AB_2687285 (BioLegend Cat. No. 698202)
Antigen Details
- Structure
- Ig superfamily, 81 kD. Six N-glycosylation sites, apparent Mw is 90-110kD.
- Distribution
-
Plasma membrane of bone marrow stromal cells, myeloid progenitors, splenic dendritic cells, activated endothelial cells
- Function
- Important in cell-cell recognition. Function in leukocyte-endothelial cell adhesion.
- Interaction
- Leukocytes
- Ligand/Receptor
- VLA-4 (α4/β1 integrin) and LPAM-1 (α4/β7 integrin)
- Biology Area
- Cell Adhesion, Cell Biology, Immunology, Innate Immunity, Signal Transduction
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1. Barclay AN, et al. 1997. The Leukocyte Antigen FactsBook Academic Press.
2. Kinashi T, et al. 1995. J. Leuko. Biol. 57:168.
3. Bevilacqua MP. 1993. Annu. Rev. Immunol. 11:767.
4. Koni PA, et al. 2001. J. Exp. Med. 193:741. - Gene ID
- 7412 View all products for this Gene ID
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