Product Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Recombinant human Serpin E1
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
IHC-P - Quality tested
WB - Verified - Recommended Usage
Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining.?For immunohistochemistry, a concentration range of 1.0 - 10.0 ?g/mL is suggested.?For western blotting, the suggested use of this reagent is 0.25 - 1.0??g/mL. It is recommended that the reagent be titrated for optimal performance for each application.?
- Application Notes
Clone A16081E is not suitable for ICC.
Antigen Details
- Structure
- Serpin E1 is a 402 amino-acid protein with a predicted molecular weight of 45 kD.
- Distribution
-
Cytoplasmic, secreted
- Function
- Serpins bind to and inhibit proteinases
- Interaction
- Serpin E1 binds to and inhibits urokinase and tissue plasminogen activator.
- Biology Area
- Cardiovascular Biology, Cell Adhesion, Inhibitory Molecules
- Antigen References
-
- van Mourik JA, et al. 1984. J Biol Chem. 259:14914-21.
- Zhou A, et al. 2003. Nat Struct Biol. 10:541-4.
- Tsantes AE, et al. 2008. Thromb Res. 122:736-42.
- Dupon DM, et al. 2009. Front Biosciences 14:1337-61.
- Ploplis VA. 2011. Curr Drug Targets. 12:1782-9.
- Yasar Yildiz S, et al. 2014. Scientific World Journal. 2014:858293.
- Gene ID
- 5054 View all products for this Gene ID
- UniProt
- View information about Serpin E1 on UniProt.org
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