Product Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Recombinant Human VEGFR2-Fc Chimera
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with Brilliant Violet 421? under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?L per million cells in 100 ?L staining volume or 5 ?L per 100 ?L of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Brilliant Violet 421? excites at 405 nm and emits at 421 nm. The standard bandpass filter 450/50 nm is recommended for detection. Brilliant Violet 421? is a trademark of Sirigen Group Ltd.
Learn more about Brilliant Violet?.
This product is subject to proprietary rights of Sirigen Inc. and is made and sold under license from Sirigen Inc. The purchase of this product conveys to the buyer a non-transferable right to use the purchased product for research purposes only. This product may not be resold or incorporated in any manner into another product for resale. Any use for therapeutics or diagnostics is strictly prohibited. This product is covered by U.S. Patent(s), pending patent applications and foreign equivalents.- Excitation Laser
- Violet Laser (405 nm)
- Application Notes
This clone does not cross-react with mouse endothelial cells.
- Product Citations
-
- RRID
- AB_2832739 (BioLegend Cat. No. 393009) AB_2832740 (BioLegend Cat. No. 393010)
Antigen Details
- Structure
- Type I transmembrane glycoprotein, type III tyrosine kinase receptor, CSF-1/PDGF receptor family
- Distribution
-
Endothelial cells, embryonic tissues
- Function
- VEGFR2 regulates angiogenesis as well as vascular development and permeability.
- Ligand/Receptor
- VEGF-A, VEGF-C, and VEGF-D splice isoforms
- Cell Type
- Endothelial cells
- Biology Area
- Angiogenesis, Cell Biology, Immunology
- Molecular Family
- CD Molecules, Cytokine/Chemokine Receptors
- Antigen References
-
- DiSalvo J, et al. 1995. J Biol Chem. 270:7717.
- McColl BK, et al. 2003. J Exp Med. 198:863.
- Albuquerque RJ, et al. 2009. Nat Med. 15:1023.
- Guangqi E, et al. 2012. J Biol Chem. 287:3029.
- Koch S, and Claesson-Welsh. 2012. Cold Spring Harb Perspect Med. 2:a006502.
- Munaut C, et al. 2012. Plos One. 7:e33475.
- Wehland M, et al. 2013. Int J Mol Sci. 14:9338.
- Gene ID
- 3791 View all products for this Gene ID
- UniProt
- View information about CD309 on UniProt.org