Product Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Recombinant human VISTA protein
- Formulation
- 0.2 ?m filtered in phosphate-buffered solution, pH 7.2, containing no preservative. Endotoxin level is < 0.01 EU/?g of the protein (< 0.001 ng/?g of the protein) as determined by the LAL test.
- Preparation
- The Ultra-LEAF? (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
- Concentration
- The antibody is bottled at the concentration indicated on the vial, typically between 2 mg/mL and 3 mg/mL. To obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C. This Ultra-LEAF? solution contains no preservative; handle under aseptic conditions.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 ?g per million cells in 100 ?L volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
Clone A17002E can completely block the binding of clone A17002B on target cells.
Clone A17002E can reduce T cell proliferation in an in vitro T cell activation assay.- RRID
- AB_2928033 (BioLegend Cat. No. 380003)
Antigen Details
- Structure
- Ig V-domain like
- Distribution
-
Hematopoietic cells, monocytes, macrophages, dendritic cell, granulocytes, subsets of T cells
- Function
- Suppressing T cell activation
- Cell Type
- Dendritic cells, Granulocytes, Lymphocytes, Macrophages, Monocytes, T cells
- Biology Area
- Immunology, Inhibitory Molecules
- Antigen References
-
- Wang Li, et al. 2011. J Exp Med. 208:577-92.
- Nowak EC, et al. 2017. Immunol Rev. 276:66-79.
- Flies DB, et al. 2014. J Clin Invest. 124:1966-75.
- Gene ID
- 64115 View all products for this Gene ID
- UniProt
- View information about VISTA on UniProt.org
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