Product Details
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Recombinant mouse Chil3
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
WB - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 2.0 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
- AB_2750120 (BioLegend Cat. No. 853801) AB_2750121 (BioLegend Cat. No. 853802)
Antigen Details
- Structure
- Chil3 is a 398 amino acid protein with a molecular weight mass of ~45 kD.
- Distribution
-
Tissue distribution: Spleen, macrophages, and bone marrow-derived neutrophils.
Cellular distribution: Nucleus, endoplasmic reticulum, and secreted. - Function
- Chil3 plays a role in hydrolysis of terminal non-reducing N-acetyl-D-hexosamine residues in N-acetyl-beta-D-hexosaminides.
- Interaction
- Chil3 binds to chitin, lectin, and heparin.
- Cell Type
- Macrophages, Neutrophils
- Biology Area
- Cell Biology, Neuroinflammation, Neuroscience, Neuroscience Cell Markers
- Molecular Family
- Enzymes and Regulators
- Antigen References
-
- Mesci P, et al. 2015. Brain. 138:53-68
- Wu F, et al. 2016. Parasitol Res. 115:3737
- Al-Rubaie A, et al. 2018. Respir Res. 19:114
- Gene ID
- 12655 View all products for this Gene ID
- UniProt
- View information about Chil3 on UniProt.org
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