Product Details
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Recombinant mouse CD218a
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
- Concentration
- 0.2 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.125??g per million cells in 100 ?L volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- RRID
- AB_2860732 (BioLegend Cat. No. 157903) AB_2860733 (BioLegend Cat. No. 157904)
Antigen Details
- Structure
- An IL-1 receptor super family member
- Distribution
-
Expressed on T cells, NK cell subset, neutrophils, IL-12 stimulated tonsillar B cells, and intestinal epithelial cells (IEC).
- Function
- Bind to pro inflammatory cytokine IL-18 and play an important role in innate and autoimmune responses.
- Ligand/Receptor
- IL-18
- Cell Type
- B cells, Endothelial cells, Neutrophils, NK cells, T cells
- Biology Area
- Immunology, Innate Immunity
- Molecular Family
- CD Molecules, Cytokine/Chemokine Receptors
- Antigen References
-
- Parnet P, et al. 1996. J. Biol. Chem. 271:3967.
- Thomassen E, et al. 1998. J. Interferon Cytokine Res. 18:1077-88.
- Debets R, et al. 2000. J. Immunol. 165:4950-6.
- Smeltz RB, et al. 2001. J. Exp. Med. 194:143-53.
- Gene ID
- 16182 View all products for this Gene ID
- UniProt
- View information about CD218a on UniProt.org
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