Product Details
- Verified Reactivity
- Human, Mouse, Rat
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
WB - Quality tested
IHC-P - Verified - Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.1 - 1.0 ?g per ml.?For immunohistochemistry on formalin-fixed paraffin-embedded tissue, a concentration range of 0.2 - 2.0 ?g/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
- AB_2783462 (BioLegend Cat. No. 856701)
Antigen Details
- Structure
- PAK1 is a 545 amino acid protein with an apparent molecular mass of ~ 61 kD.
- Distribution
-
Tissue distribution: Ubiquitously expressed in all tissues.
Cellular distribution: Cytosol, plasma membrane, and nucleus.
- Function
- PAK1 plays an important role in regulating cytoskeletal dynamics, spine morphology, and synaptic plasticity.
- Interaction
- Forms homodimer, NISCH, DVL1, MUSK, CDC2L1, CDC2L2, p110C, CDC42/P21, RAC1, DSCAM, PDPK1, RAF1, NCK1, NCK2
- Cell Type
- Astrocytes, Microglia, Neurons, Oligodendrocytes
- Biology Area
- Neuroscience, Synaptic Biology
- Molecular Family
- Postsynaptic proteins
- Antigen References
-
- Xia S, et al. 2018. Small GTPases. 9(4):322
- Kreis P, et al. 2009. Cell Signal. 21(3):384
- Nikolic M. 2008. Mol Neurobiol. 37(2-3): 187
- Salminen A, et al. 2008. Biochem Biophys Res Commun. 371(4):587
- Gene ID
- 5058 View all products for this Gene ID 18479 View all products for this Gene ID 29431 View all products for this Gene ID
- UniProt
- View information about PAK1 on UniProt.org
我要詢價(jià)
*聯(lián)系方式：
(可以是QQ、MSN、電子郵箱、電話等，您的聯(lián)系方式不會(huì)被公開)
*內(nèi)容：
