Product Details
- Verified Reactivity
- Human, Rat
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Recombinant human Rab6A
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
WB - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.5 - 1.0 ?g per mL. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
The antibody also detects mouse Rab6 A & B. In mouse brain lysates, besides band corresponding to Rab6, it also detects a band at ~50kD that was stronger than the isotype control.
- RRID
- AB_2820174 (BioLegend Cat. No. 868901) AB_2820175 (BioLegend Cat. No. 868902)
Antigen Details
- Structure
- RAB6 is a 208 amino acid protein with predicted and observed molecular mass of ~ 25 kD.
- Distribution
-
Tissue Distribution: Ubiquitously expressed
Cellular Distribution: Cytosol, Golgi apparatus, plasma membrane, and endoplasmic reticulum - Function
- Rab6 plays a role in retrograde protein transportation from the plasma membrane to the Golgi apparatus, and the endoplasmic reticulum.
- Interaction
- RAB6IP1, RAB6KIFL, BICD1, BICD2, TMF1, DYNLRB1
- Cell Type
- Neurons
- Biology Area
- Neurodegeneration, Neuroinflammation, Neuroscience, Neuroscience Cell Markers, Protein Trafficking and Clearance, Synaptic Biology
- Molecular Family
- Golgi Markers, Organelle Markers, Postsynaptic proteins, Presynaptic proteins, Synaptic Vesicle Trafficking/Endocytosis
- Antigen References
-
- Liu S, et al. 2015. Int Rev Cell Mol Biol. 315:1
- Heffernan LF, et al. 2014. Biochem Soc Trans. 42(5):1453
- Fernandes H, et al. 2009. Biochem Soc Trans. 37:1037
- Gene ID
- 5870 View all products for this Gene ID 51560 View all products for this Gene ID 84379 View all products for this Gene ID 363123 View all products for this Gene ID
- UniProt
- View information about Rab4 on UniProt.org
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