Product Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Recombinant human CD166 protein
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25??g per million cells in 100 ?L volume. It is recommended that the reagent be titrated for optimal performance for each application.
Antigen Details
- Structure
- Type I transmembrane glycoprotein belonging to the Ig superfamily of proteins
- Distribution
-
CD166 is expressed on activated T cells, activated monocytes, epithelial cells, fibroblasts, and neurons
- Function
- Play an important role in mediating adhesion interactions between thymic epithelial cells and CD6+ cells during intrathymic T cell development
- Ligand/Receptor
- CD6
- Cell Type
- Granulocytes, Monocytes, T cells
- Biology Area
- Cell Adhesion, Immunology, Stem Cells
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
- Aruffo A, et al. 1997. Immunol Today. 18:498-504.
- Bowen MA, et al. 1995. J Exp Med. 181:2213-20.
- Patel DD, et al. 1995. J Exp Med. 181:1563-8.
- Horst D, et al. 2009. Cancer Invest. 27:844-50.
- Gene ID
- 214 View all products for this Gene ID
- UniProt
- View information about CD166 on UniProt.org
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