Product Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Recombinant human CD166
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
IHC-P - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 5 - 10 ?g/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
- Product Citations
-
- RRID
- AB_2814379 (BioLegend Cat. No. 397802)
Antigen Details
- Structure
- A type I transmembrane glycoprotein belonging to the Ig superfamily of proteins.
- Distribution
-
CD166 is expressed on activated T cells, activated monocytes, epithelial cells, fibroblasts, and neurons.
- Function
- Play an important role in mediating adhesion interactions between thymic epithelial cells and CD6+ cells during intrathymic T cell development.
- Ligand/Receptor
- CD6
- Cell Type
- B cells, Dendritic cells, Mesenchymal Stem Cells, Tregs
- Biology Area
- Cell Biology
- Molecular Family
- CD Molecules
- Antigen References
-
- Aruffo A, et al. 1997. Immunol Today. 18(10):498.
- Patel DD, et al. 1995. J. Exp. Med. 181:2213.
- Bowen MA, et al. 1995. J. Exp. Med. 181:1563.
- Horst D, et al. 2009. Cancer Invest. 8:844-50.
- Gene ID
- 214 View all products for this Gene ID
- UniProt
- View information about CD166 on UniProt.org