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Purified anti-human CD166 Antibody

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Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Recombinant human CD166
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

IHC-P - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 5 - 10 ?g/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.

Product Citations
  1. Ceccarelli S, et al. 2022. Front Cell Dev Biol. 10:926180. PubMed
RRID
AB_2814379 (BioLegend Cat. No. 397802)

Antigen Details

Structure
A type I transmembrane glycoprotein belonging to the Ig superfamily of proteins.
Distribution

CD166 is expressed on activated T cells, activated monocytes, epithelial cells, fibroblasts, and neurons.

Function
Play an important role in mediating adhesion interactions between thymic epithelial cells and CD6+ cells during intrathymic T cell development.
Ligand/Receptor
CD6
Cell Type
B cells, Dendritic cells, Mesenchymal Stem Cells, Tregs
Biology Area
Cell Biology
Molecular Family
CD Molecules
Antigen References
  1. Aruffo A, et al. 1997. Immunol Today. 18(10):498.
  2. Patel DD, et al. 1995. J. Exp. Med. 181:2213.
  3. Bowen MA, et al. 1995. J. Exp. Med. 181:1563.
  4. Horst D, et al. 2009. Cancer Invest. 8:844-50.
Gene ID
214 View all products for this Gene ID
UniProt
View information about CD166 on UniProt.org
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