Product Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Full-length recombinant human Galectin-1
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
WB - Quality tested
IHC-P - Verified - Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 5.0?- 10??g per ml. For immunohistochemistry on formalin-fixed paraffin-embedded tissue sections, a concentration range of 5.0?- 10??g/ml is suggested.?It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
- AB_2814612 (BioLegend Cat. No. 867301) AB_2814613 (BioLegend Cat. No. 867302)
Antigen Details
- Structure
- Galectin 1 is a 135 amino acid protein with predicted and observed molecular mass of ~15 kD.
- Distribution
-
Tissue Distribution: Smooth muscle, placenta, endometrium, adipose tissue, and soft tissue
Cellular Distribution: Endoplasmic reticulum, cytosol, nucleus, plasma membrane, and extracellular
- Function
- Galectin 1 binds to β-galactoside and is involved in regulating apoptosis, cell proliferation, and differentiation.
- Interaction
- Galectin 1 forms homodimers and binds to LGALS3BP, GEMIN4, HRAS, Laminin, SUSD2.
- Cell Type
- Microglia
- Biology Area
- Cancer Biomarkers, Neurodegeneration, Neuroinflammation, Neuroscience, Neuroscience Cell Markers
- Antigen References
-
- Gajiwala S, et al. 2018. J. Gastrointest. Oncol. 9:1014-26.
- Seropian IM, et al. 2018. Mediators Inflamm. 2018:8696543.
- Brinchmann MF, et al. 2018. Mediators Inflamm. 2018:9186940.
- Gene ID
- 2956 View all products for this Gene ID
- UniProt
- View information about Galectin-1 on UniProt.org