Product Details
- Verified Reactivity
- Human, Mouse, Rat
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Recombinant human RCAN1
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
WB - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 2 - 10 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
- AB_2814606 (BioLegend Cat. No. 866201) AB_2814607 (BioLegend Cat. No. 866202)
Antigen Details
- Structure
- RCAN1 is a 252 amino acid protein with predicted molecular mass of ~ 28 kD, and observed molecular masses of ~ 35 kD (RCAN1L) and ~24 kD (RCAN1S) by WB.
- Distribution
-
Tissue Distribution: Ubiquitously expressed
Cellular Distribution: Nucleus and Cytosol - Function
- RCAN1 inhibits the calcineurin/NFAT signaling pathway
- Interaction
- RAF1, PPP3CA, PPP3R1, Calcineurin A
- Cell Type
- Microglia
- Biology Area
- Cell Biology, Neurodegeneration, Neuroscience, Signal Transduction, Synaptic Biology
- Antigen References
-
- Porta S, et al. 2007. Hum Mol Genet. 16(9):1039
- Torac E, et al. 2014. J Med Life. 7(4):481
- Wu Y, et al. 2014, Mol Neurobiol. 50(3):1085
- Harris CD, et al. 2005. Cell Mol Life Sci. 62(21):2477
- Gene ID
- 1827 View all products for this Gene ID 54720 View all products for this Gene ID 266766 View all products for this Gene ID
- UniProt
- View information about RCAN1 on UniProt.org
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