Product Details
- Verified Reactivity
- Human, Mouse, Rat
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography and conjugated with Alexa Fluor? 488 under optimal conditions.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
IHC-P - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 5.0?- 10??g/mL is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
* Alexa Fluor? 488 has a maximum emission of 519 nm when it is excited at 488 nm.
Alexa Fluor? and Pacific Blue? are trademarks of Life Technologies Corporation.
View full statement regarding label licenses- Excitation Laser
- Blue Laser (488 nm)
- RRID
- AB_2861087 (BioLegend Cat. No. 862709) AB_2861088 (BioLegend Cat. No. 862710)
Antigen Details
- Structure
- RBFOX1 is a 416 amino acid protein with an apparent molecular mass of ~ 45 kD.
- Distribution
-
Tissue Distribution: brain and heart.
Cellular Distribution: nucleus, golgi apparatus, and cytosol. - Function
- RBFOX1 is an RNA binding protein that modulates mRNA alternative splicing.
- Interaction
- RNA, ataxin-2
- Cell Type
- Neurons, Oligodendrocytes
- Biology Area
- Neurodegeneration, Protein Synthesis, Transcription Factors
- Antigen References
-
- Wang ET, et al. 2016. J. Neurosci. 36(45):11418
- Duan W, et al. 2016. Mol Neurobiol. 53(3):1637
- Kuroyanagi H, 2009. Cell Mol Life Sci. 66(24):3895
- Gene ID
- 54715 View all products for this Gene ID 268859 View all products for this Gene ID 302920 View all products for this Gene ID
- UniProt
- View information about RBFOX1 on UniProt.org