Product Details
- Verified Reactivity
- Human, Mouse, Rat
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
WB - Quality tested
IHC-P - Verified - Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.1 - 0.5 ?g per ml. For immunohistochemistry, a concentration range of 5 - 10 ?g/ml is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
- AB_2801247 (BioLegend Cat. No. 862701) AB_2801248 (BioLegend Cat. No. 862702)
Antigen Details
- Structure
- RBFOX1 is a 416 amino acid protein with an apparent molecular mass of ~ 45 kD.
- Distribution
-
Tissue Distribution: brain and heart.
Cellular Distribution: nucleus, golgi apparatus, and cytosol. - Function
- RBFOX1 is an RNA binding protein that modulates mRNA alternative splicing.
- Interaction
- RNA, ataxin-2
- Cell Type
- Neurons, Oligodendrocytes
- Biology Area
- Neurodegeneration, Protein Synthesis, Transcription Factors
- Antigen References
-
- Wang ET, et al. 2016. J. Neurosci. 36(45):11418
- Duan W, et al. 2016. Mol Neurobiol. 53(3):1637
- Kuroyanagi H, 2009. Cell Mol Life Sci. 66(24):3895
- Gene ID
- 54715 View all products for this Gene ID 268859 View all products for this Gene ID 302920 View all products for this Gene ID
- UniProt
- View information about RBFOX1 on UniProt.org
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