Product Details
- Verified Reactivity
- Human, Mouse, Rat
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Recombinant human Rab8A
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
WB - Quality tested
ICC - Verified - Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 1 - 5 ?g per ml. For immunocytochemistry, a concentration range of 1 - 5 μg/ml is recommended. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
This clone cross-react with Rab8A and Rab8B.
- RRID
- AB_2810773 (BioLegend Cat. No. 865401) AB_2810774 (BioLegend Cat. No. 865402)
Antigen Details
- Structure
- Rab8 is a 207 amino acid protein with an apparent molecular mass of ~24 kD.
- Distribution
-
Tissue Distribution: ubiquitously expressed
Cellular Distribution: Plasma membrane, cytoskeleton, cytosol, Golgi Apparatus, and endosome. - Function
- Rab8 is a GTPase that plays an important role in intracellular membrane trafficking.
- Interaction
- MICALL1, MICALL2, Optineurin, MAP4K2
- Cell Type
- Astrocytes, Dopaminergic Neurons, GABAergic Neurons, Glutamatergic Neurons, Mature Neurons, Microglia, Neural Stem Cells, Neurons, Oligodendrocytes
- Biology Area
- Cancer Biomarkers, Cell Biology, Cell Cycle/DNA Replication, Neurodegeneration, Neuroscience, Protein Misfolding and Aggregation, Protein Trafficking and Clearance, Synaptic Biology
- Molecular Family
- Autophagosome Markers, Cytoskeletal Proteins, Organelle Markers, Tumor Suppressors
- Antigen References
-
- Zhang X and Gao N. 2016. Small GTPases. 7:59
- Just WW and Per?nen J. 2016. Biochim Biophys Acta. 1863:1006
- Ao X, et al. 2014. Cell Death Differ. 21(3):348
- Corbier C and Sellier C. 2017. Small GTPases. 8:181
- Gene ID
- 4218 View all products for this Gene ID 17274 View all products for this Gene ID 117103 View all products for this Gene ID
- UniProt
- View information about RAB8 on UniProt.org
我要詢價(jià)
*聯(lián)系方式：
(可以是QQ、MSN、電子郵箱、電話等，您的聯(lián)系方式不會被公開)
*內(nèi)容：
