Product Details
- Verified Reactivity
- Human, Mouse, Rat
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- KLH-conjugated C-terminal peptide of mouse SLC6A1.
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
WB - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 2.0 - 10 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
Avoid boiling lysates before loading to SDS for WB.
- RRID
- AB_2810801 (BioLegend Cat. No. 867401) AB_2810802 (BioLegend Cat. No. 867402)
Antigen Details
- Structure
- GAT1 is a 599 amino acid protein with predicted and observed molecular mass of ~ 67 kD.
- Distribution
-
Tissue Distribution: Brain
Cellular Distribution: Plasma membrane - Function
- GAT1 is a GABA transporter protein that removes excessive GABA from the synaptic cleft and the extrasynaptic space.
- Interaction
- MPP5, STX1A
- Ligand/Receptor
- GABA
- Cell Type
- Astrocytes, GABAergic Neurons, Mature Neurons, Neurons, Oligodendrocytes
- Biology Area
- Neurodegeneration, Neuroinflammation, Neuroscience, Neuroscience Cell Markers, Synaptic Biology
- Molecular Family
- Neurotransmitter Receptor Trafficking/Endocytosis, Presynaptic proteins, Synaptic Vesicle Trafficking/Endocytosis
- Antigen References
-
- Zafar S, et al. 2018. Front Chem. 6:397.
- Lie MEK, et al. 2017. Adv. Neurobiol. 16:137-167.
- Zhou Y, Danbolt NC. 2013. Front Endocrinol (Lausanne). 4:165.
- Gene ID
- 6529 View all products for this Gene ID 232333 View all products for this Gene ID 79212 View all products for this Gene ID
- UniProt
- View information about SLC6A1 on UniProt.org
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