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Purified anti-GlyT2 (SLC6A5) Antibody

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Product Details

Verified Reactivity
Human, Mouse, Rat
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Synthetic peptide corresponding to a.a. 182-199 of mouse SLC6A5
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

WB - Quality tested
ICC - Verified

Recommended Usage

Each lot of this antibody is quality control tested by western blotting. For western blotting, the suggested use of this reagent is 1 - 5 ?g/mL. For immunocytochemistry, a concentration range of 2 - 10 μg/mL is recommended. It is recommended that the reagent be titrated for optimal performance for each application.

RRID
AB_2820198 (BioLegend Cat. No. 870801) AB_2820199 (BioLegend Cat. No. 870802)

Antigen Details

Structure
GlyT2 is a 797 amino acid protein with predicted and observed molecular mass of ~87 kD.
Distribution

Tissue Distribution: Brain
Cellular Distribution: Plasma Membrane

Function
Glycine transport and recycling
Ligand/Receptor
Glycine
Cell Type
Mature Neurons, Neurons
Biology Area
Cell Biology, Neurodegeneration, Neuroinflammation, Neuroscience, Neuroscience Cell Markers
Molecular Family
Neurotransmitter Receptor Trafficking/Endocytosis, Presynaptic proteins
Antigen References
  1. Zafra F, et al. 2017. Adv Neurobiol. 16:55.
  2. Lopez-Corcuera B, et al. 2017. Adv Neurobiol. 16:13.
  3. Vandenberg RJ, et al. 2014. Trends Pharmacol Sci. 35(8):423.
Gene ID
9152 View all products for this Gene ID 171148 View all products for this Gene ID
UniProt
View information about GlyT2 on UniProt.org
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