Product Details
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Recombinant mouse CD27 protein
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.5??g per million cells in 100 ?L volume. It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
Clone A18209B can compete with clone LG.3A10 on target cells.
Clone A18209B can also block binding of CD70 to CD27 in a cell-based binding assay.- RRID
- AB_2910285 (BioLegend Cat. No. 110102)
Antigen Details
- Structure
- TNFR superfamily, 45 kD
- Distribution
-
Peripheral blood T cells, memory B cells, NK cells, thymocytes subset
- Function
- Costimulatory signal for T and B cell activation, T cell development
- Interaction
- TRAF2, TRAF5, CD27-binding protein (Siva)
- Ligand/Receptor
- CD70
- Cell Type
- B cells, Lymphocytes, T cells, Thymocytes
- Biology Area
- Adaptive Immunity, Costimulatory Molecules, Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
- Hintzen RQ, et al. 1994. Immunol. Today 15:307-11.
- Akiba H, et al. 1998. J. Biol. Chem. 273:13353-8.
- Kobata T, et al. 1995. P. Natl. Acad. Sci. USA 92:11249-53.
- Camerini D, et al. 1991. J. Immunol. 147:3165-9.
- Gene ID
- 21940 View all products for this Gene ID
- UniProt
- View information about CD27 on UniProt.org
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