Product Details
- Verified Reactivity
- Human, Mouse
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Recombinant human NSE
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
WB - Quality tested
IHC-P - Verified - Recommended Usage
Each lot of this antibody is quality control tested by western blotting. For western blotting, the suggested use of this reagent is 1.0 - 10.0 ?g/mL. For immunohistochemistry on formalin-fixed paraffin-embedded tissue sections, a concentration range of 1.0 - 10.0 ?g/mL is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
- AB_2924615 (BioLegend Cat. No. 605751) AB_2924615 (BioLegend Cat. No. 605752)
Antigen Details
- Structure
- Gamma enolase is a 434 amino acid protein with a molecular mass of 47 kD.
- Distribution
-
Tissue distribution: Nervous and musculoskeletal systems.
Cellular distribution: Secreted, cytosol, plasma membrane, cytoskeleton, and nucleus. - Function
- Gamma enolase has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. It binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival.
- Cell Type
- Mature Neurons, Neurons
- Biology Area
- Neuroscience, Neuroscience Cell Markers
- Molecular Family
- Enzymes and Regulators
- Antigen References
-
- Murray GI, et al. 1993. J Clin Pathol. 46:993-6.
- Duncan ME, et al. 1992. J immunol Methods. 151:2227-36.
- Gene ID
- 2026 View all products for this Gene ID
- UniProt
- View information about NSE on UniProt.org
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