Product Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Synthetic peptide of human BLNK (phosphorylated at Tyr 96)
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
ICFC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?L per million cells in 100 ?L staining volume or 5 ?L per 100 ?L of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- RRID
- AB_2924580 (BioLegend Cat. No. 382203) AB_2924580 (BioLegend Cat. No. 382204)
Antigen Details
- Structure
- Human BLNK is 456 amino acids (aa) in length and it contains a Pro?rich region (aa 98?260) and one SH2 domain (aa 346?453).
- Distribution
-
Cytosol, plasma-membrane associated, B cells
- Function
- Links B cell receptor engagement with downstream signaling events
- Interaction
- PLCG1, PLCG2, VAV1, NCK1, VAV3, GRB2, FYN, LYN, SYK
- Molecular Family
- Phospho-Proteins
- Antigen References
-
- Fu C, et al. 1998. Immunity 9:93-103.
- Ishiai M, et al. 1999. Immunity 10:117-25.
- Baba Y, et al. 2001. Proc. Natl. Acad. Sci. USA 98:2582-6.
- Tsuji S, et al. 2001. J. Exp. Med. 194:529-39.
- Chiu CW, et al. 2002. EMBO. J. 21:6461-72.
- Taguchi T, et al. 2004. Immunology. 122:575-82.
- Gene ID
- 29760 View all products for this Gene ID
- UniProt
- View information about BLNK Phospho Tyr96 on UniProt.org
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