Product Details
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Recombinant mouse CD255 protein
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 ?g per million cells in 100 ?L volume. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
- AB_2927914 (BioLegend Cat. No. 119102)
Antigen Details
- Structure
- TNF superfamily member; type II membrane protein and secreted; homotrimer, 27 kD
- Distribution
-
Widely expressed; induced on activated CD4+ cells
- Function
- Weak inducer of apoptosis in some cell types, activates NF-κB, promotes angiogenesis and endothelial cell proliferation, induces inflammatory cytokine production
- Ligand/Receptor
- TWEAKR/FN14
- Cell Type
- T cells
- Biology Area
- Angiogenesis, Apoptosis/Tumor Suppressors/Cell Death, Cell Biology, Immunology
- Molecular Family
- CD Molecules
- Antigen References
-
- Chicheportiche Y, et al. 1997. J. Biol. Chem. 272:32401-10.
- Schneider P, et al. 1999. Eur. J. Immunol. 29:1785-92.
- Gene ID
- 21944 View all products for this Gene ID
- UniProt
- View information about CD255 on UniProt.org
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