Product Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
IHC-P - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry, a concentration range of 5.0 - 10.0 ?g/mL is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
- AB_2910445 (BioLegend Cat. No. 379302)
Antigen Details
- Structure
- Transmembrane TNF superfamily receptor, contains no death domain, 14 kD
- Distribution
-
Widely expressed in heart, placenta, lung, muscle, kidney, pancreas, and HUVEC
- Function
- Binds to TWEAK (CD255), thought to play a role in cell death and inflammation
- Ligand/Receptor
- TWEAK (CD255); interacts with cytoplasmic proteins TRAF1, 2, and 3
- Antigen References
-
- Feng SL, et al. 2000. Am J Pathanol. 156:1253-61.
- Meighan-Mantha RL, et al. 1999. J Biol Chem. 274:33166-79.
- Nakayama M, et al. 2003. J Immunol. 170:341-8.
- Lynch CN, et al. 1999. J Biol Chem. 274:8455-9.
- Gene ID
- 51330 View all products for this Gene ID
- UniProt
- View information about CD266 on UniProt.org
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