Product Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25??g per million cells in 100 ?L volume. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
- AB_2927851 (BioLegend Cat. No. 383902)
Antigen Details
- Structure
- The protein consists of 976 a.a. with a molecular weight of 108 kD.
- Distribution
-
Cytoplasmic and membranous expression in most tissues, including parathyroid gland
- Function
- Kinase, receptor, transferase, tyrosine-protein kinase. EphA1/A2 and ephrin‐A1 are over‐expressed or downregulated in various types of cancer.
- Interaction
- EphA1/A2 and ephrin‐A1 are correlated with tumor malignancy and prognosis.
- Ligand/Receptor
- Ephrin-A1
- Cell Type
- B cells, Endothelial cells, Epithelial cells, T cells, Thymocytes
- Biology Area
- Cancer Biomarkers, Cell Adhesion, Immunology
- Molecular Family
- Protein Kinases/Phosphatase
- Antigen References
-
- Katsuaki L and Yoshiro M. 2019. Cancer Sci. 110:841.
- Holen L, et al. 2010. J Leukoc Biol. 87:1059-68.
- Gene ID
- 2041 View all products for this Gene ID
- UniProt
- View information about EphA1 on UniProt.org
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