Product Details
- Verified Reactivity
- Mouse
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Recombinant protein (val 24-val 563 extracellular domain)
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
FC - Quality tested
IHC-F - Verified - Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25??g per million cells in 100 ?L volume. For immunohistochemistry on frozen tissue sections, a concentration range of 5.0 - 10.0 ?g/mL is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
- AB_2927860 (BioLegend Cat. No. 112102)
Antigen Details
- Structure
- CD146 is a transmembrane glycoprotein and belongs to the Ig superfamily of cell adhesion molecules.
- Distribution
-
CD146 is strongly expressed by murine vascular endothelial cells, a subset of NK1.1+ cells, and neutrophils.
- Function
- CD146 has been reported to be functionally relevant for endothelial cell adhesion, angiogenesis, and NK cell function.
- Ligand/Receptor
- Unidentified ligand
- Cell Type
- Endothelial cells, Epithelial cells, Mesenchymal cells, Mesenchymal Stem Cells, T cells
- Biology Area
- Cell Biology, Immunology, Innate Immunity, Neuroscience, Neuroscience Cell Markers, Stem Cells
- Molecular Family
- Adhesion Molecules, CD Molecules
- Gene ID
- 84004 View all products for this Gene ID
- UniProt
- View information about CD146 on UniProt.org
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