Product Details
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/mL
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C.
- Application
-
IHC-P - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by formalin-fixed paraffin-embedded immunohistochemical staining. For immunohistochemistry on formalin-fixed paraffin-embedded tissue sections, a concentration range of?5.0 - 10.0 ?g/mL is suggested. It is recommended that the reagent be titrated for optimal performance for each application.
- RRID
- AB_2927842 (BioLegend Cat. No. 381102)
Antigen Details
- Structure
- 462 amino acid protein with a molecular mass of 63 kD
- Distribution
-
Tissue Distribution: liver
Cellular Distribution: plasma membrane, nucleus, cytosol, lysosome, and endosome - Function
- Binds to free heme in blood vessel for iron homeostasis
- Interaction
- LRP1
- Ligand/Receptor
- Free heme
- Biology Area
- Cell Biology, Cell Death, Neuroscience
- Molecular Family
- APP/β-Amyloid, APP/Aβ Degradation, Apolipoproteins
- Antigen References
-
- Altruda F, et al. 1988. J Mol Evol. 27:102-8.
- Watanabe J, et al. 2009. J Biol Chem. 284:18292-301.
- Yang Z, et al. 2010. J Biol Chem. 285:28874-82.
- Gene ID
- 3263 View all products for this Gene ID
- UniProt
- View information about Hemopexin on UniProt.org
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