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Purified anti-human CD209 (DC-SIGN) Antibody

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Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Rat
Immunogen
Recombinant human CD209 protein, extracellular domain.
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 ?g per million cells in 100 ?L volume. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

Clone A20120B can partially block the binding of clone 9E9A8 to target. It does not affect the binding of clone DCS-8C1, clone A20120F, and clone 14E3G7.

RRID
AB_2924571 (BioLegend Cat. No. 380402)

Antigen Details

Structure
A 44 kD type II transmembrane glycoprotein and a member of the C-type lectin family
Distribution

Dendritic cells, Endothelial cells, Macrophages

Function
Functions in cell adhesion and pathogen recognition. This receptor recognizes a wide range of evolutionarily divergent pathogens with a large impact on public health, including leprosy and tuberculosis mycobacteria, the Ebola, hepatitis C, HIV-1 and Dengue viruses, and the SARS-CoV acute respiratory syndrome coronavirus.
Cell Type
Dendritic cells
Biology Area
Immunology, Innate Immunity
Molecular Family
CD Molecules
Antigen References
  1. Fauci A. 1996. Nature. 384:529-34.
  2. Granelli-Piperno A, et al. 2005. J Immunol. 175:4265-73. 
  3. Lai WK, et al. 2006. Am J Pathol. 169:200-8.
Gene ID
30835 View all products for this Gene ID
UniProt
View information about CD209 on UniProt.org
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