Product Details
- Verified Reactivity
- Mouse, Human
- Antibody Type
- Monoclonal
- Host Species
- Rat
- Immunogen
- Mature recombinant protein mouse Interleukin-22 (Leu34-Val179)
- Formulation
- This antibody is provided in phosphate-buffered solution, pH 7.2, 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- Upon receipt, store undiluted between 2°C and 8°C.
- Application
-
WB - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by Western blotting. Western blotting, suggested working dilution(s): Use 0.5 ?g/ml dilution buffer for each mini-gel.
- Application Notes
Clone BL35175 has been shown to be useful for detecting mouse and human IL-22 by Western blotting.
- Product Citations
-
- RRID
- AB_10695475 (BioLegend Cat. No. 517501) AB_10694243 (BioLegend Cat. No. 517502)
Antigen Details
- Structure
- 179 aa with with a putative 33 aa signal peptide that is cleaved to generate a 147 aa mature protein.
- Distribution
-
Secreted, Th17
- Function
- Cytokine that contributes to the inflammatory response in vivo.
- Ligand/Receptor
- Binds to IL-22 receptor complex that consists of two receptor subunits, IL22R and IL10Rβ.
- Cell Type
- Th17
- Biology Area
- Cell Biology, Signal Transduction
- Molecular Family
- Cytokines/Chemokines
- Antigen References
-
1. Dumoutier L, et al. 2000. J. Immunol. 164:1814.
2. Xie MH, et al. 2000. J. Biol. Chem. 275:31335.
3. Jones BC, et al. 2008. Structure 16:1333.
4. Sonnenberg GF, et al. 2010. J. Exp. Med. 207:1293.
5. Kotenko SV, et al. 2001. J. Immunol. 166:7096.
6. Chang C, et al. 2006. Cell Research 16:902. - Gene ID
- 50929 View all products for this Gene ID
- UniProt
- View information about IL-22 on UniProt.org
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